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In the next step, a number of unsymmetrical azobenzenes had been screened as substrates, plus the products 43a–d and 43a’–43d’ have been acquired (Plan 13). Notably, the steric setting from the azobenzene orients the formation of preferred products 43e–file. The substrate scope of the response was further expanded to trifluoroacetaldehyde

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, 2013). Nonetheless, the usefulness of the design continues to be unclear since it was not compared to big metabolites in human urine samples. Even though the humanized mouse model is efficient, the data good quality created does not justify the superior Price tag; Furthermore, its restricted business availability stops its utilization in program